• Adherence to Guidelines for Acute Rehabilitation in the Norwegian Trauma Plan. 

      Schäfer, Christoph; Moksnes, Håkon Øgreid; Rasmussen, Mari Storli; Hellstrøm, Torgeir; Søberg, Helene L.; Røise, Olav; Røe, Cecilie; K Frisvold, Shirin; Bartnes, Kristian; Næss, Pål Aksel; Gaarder, Aslaug Christine; Helseth, Eirik; Brunborg, Cathrine; Andelic, Nada; Anke, Audny Gabriele Wagner (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-27)
      Objective: To evaluate adherence to 3 central operational recommendations for acute rehabilitation in the Norwegian trauma plan.<p> <p>Methods: A prospective multi-centre study of 538 adults with moderate and severe trauma with New Injury Severity Score >9. <p>Results: Adherence to the first recommendation, assessment by a physical medicine and rehabilitation physician within 72 h following ...
    • Care pathways and factors associated with interhospital transfer to neurotrauma centers for patients with isolated moderate-to-severe traumatic brain injury: a population-based study from the Norwegian trauma registry 

      Cuevas-Østrem, Mathias; Thorsen, Kjetil; Wisborg, Torben; Røise, Olav; Helseth, Eirik; Jeppesen, Elisabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-26)
      Background Systems ensuring continuity of care through the treatment chain improve outcomes for traumatic brain injury (TBI) patients. Non-neurosurgical acute care trauma hospitals are central in providing care continuity in current trauma systems, however, their role in TBI management is understudied. This study aimed to investigate characteristics and care pathways and identify factors associated ...
    • Comparative effectiveness of intracranial hypertension management guided by ventricular versus intraparenchymal pressure monitoring: a CENTER-TBI study 

      Volovici, Victor; Pisică, Dana; Gravesteijn, Benjamin; Dirven, Clemens M. F.; Steyerberg, Ewout W.; Ercole, Ari; Stocchetti, Nino; Nelson, David; Menon, David K; Citerio, Giuseppe; Van Der Jagt, Mathieu; Maas, Andrew I. R.; Haitsma, Iain K.; Lingsma, Hester F.; Vik, Anne; Skandsen, Toril; Andelic, Nada; Røise, Olav; Helseth, Eirik; Andreassen, Lasse; Anke, Audny Gabriele Wagner; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-01)
      <b><p>Objective</b> To compare outcomes between patients with primary external ventricular device (EVD)–driven treatment of intracranial hypertension and those with primary intraparenchymal monitor (IP)–driven treatment. <b><p>Methods</b> The CENTER-TBI study is a prospective, multicenter, longitudinal observational cohort study that enrolled patients of all TBI severities from 62 participating ...
    • Compensation claims in pediatric orthopedics in Norway between 2012 and 2018: a nationwide study of 487 patients 

      Horn, Joachim; Rasmussen, Hanne; Bukholm, Ida Rashida Khan; Røise, Olav; Terjesen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-04)
      Background and purpose — In Norway all compensation claims based on healthcare services are handled by a government agency (NPE, Norsk Pasientskade Erstatning). We provide an epidemiological overview of claims within pediatric orthopedics in Norway, and identify the most common reasons for claims and compensations.<p> <p>Patients and methods — All compensation claims handled by NPE from 2012 to ...
    • Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury 

      Mikolic, Ana; van Klaveren, David; Oude Groeniger, Joost; Wiegers, E; Lingsma, Hester F; Zeldovich, Marina; von Steinbüchel, Nicole; Maas, Andrew I.R.; Roeters van Lennep, Jeanine; Polinder, Suzanne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-19)
      Traumatic brain injury (TBI) is a significant cause of disability, but little is known about sex and gender differences after TBI. We aimed to analyze the association between sex/gender, and the broad range of care pathways, treatment characteristics, and outcomes following mild and moderate/severe TBI. We performed mixed-effects regression analyses in the prospective multi-center Collaborative ...
    • Differences in time-critical interventions and radiological examinations between adult and older trauma patients: A national register-based study 

      Cuevas-Østrem, Mathias; Wisborg, Torben; Røise, Olav; Jeppesen, Elisabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-07)
      BACKGROUND<p> <p>Older trauma patients are reported to receive lower levels of care than younger adults. Differences in clinical management between adult and older trauma patients hold important information about potential trauma system improvement targets. The aim of this study was to compare prehospital and early in-hospital management of adult and older trauma patients, focusing on time-critical ...
    • Epidemiology of geriatric trauma patients in Norway: A nationwide analysis of Norwegian Trauma Registry data, 2015-2018. A retrospective cohort study. 

      Cuevas-Østrem, Mathias; Røise, Olav; Wisborg, Torben; Jeppesen, Elisabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-04)
      <i>Introduction</i> - Geriatric patients have a high risk of poor outcomes after trauma and is a rapid-increasing group within the trauma population. Given the need to ensure that the trauma system is targeted, efficient, accessible, safe and responsive to all age groups the aim of the present study was to explore the epidemiology and characteristics of the Norwegian geriatric trauma population and ...
    • Extended Coagulation Profiling in Isolated Traumatic Brain Injury: A CENTER-TBI Analysis 

      Böhm, Julia K.; Schaeben, Victoria; Schäfer, Nadine; Güting, Helge; Lefering, Rolf; Thorn, Sophie; Schöchl, Herbert; Zipperle, Johannes; Grottke, Oliver; Rolf, Rossaint; Stanworth, Simon; Curry, Nicola; Maegele, Marc; Åkerlund, Cecilia; Amrein, Krisztina; Andelic, Nada; Andreassen, Lasse; Vik, Anne; Anke, Audny Gabriele Wagner; Antoni, Anna; Audibert, Gérard; Azouvi, Philippe; Frisvold, Shirin; Skandsen, Toril; Helseth, Eirik; Røe, Cecilie; Røise, Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-16)
      Background Trauma-induced coagulopathy in traumatic brain injury (TBI) remains associated with high rates of complications, unfavorable outcomes, and mortality. The underlying mechanisms are largely unknown. Embedded in the prospective multinational Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study, coagulation profiles beyond standard conventional ...
    • Factors associated with discharge destination from acute care after moderate-to-severe traumatic injuries in Norway: a prospective population-based study 

      Moksnes, Håkon Øgreid; Schäfer, Christoph; Rasmussen, Mari Storli; Søberg, Helene L.; Røise, Olav; Anke, Audny Gabriele Wagner; Røe, Cecilie; Næss, Pål Aksel; Gaarder, Aslaug Christine; Helseth, Eirik; DAHL, HILDE MARGRETE; Hestnes, Morten; Brunborg, Cathrine; Andelic, Nada; Hellstrøm, Torgeir (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-13)
      Background - Previous studies have demonstrated that the trauma population has needs for rehabilitation services that are best provided in a continuous and coordinated way. The discharge destination after acute care is the second step to ensuring quality of care. There is a lack of knowledge regarding the factors associated with the discharge destination for the overall trauma population. This paper ...
    • Functional Outcomes at 6 and 12 Months Post-Injury in a Trauma Centre Population with Moderate-to-Severe Traumatic Injuries 

      Moksnes, Håkon Øgreid; Schafer, C.; Rasmussen, Mari Storli; Søberg, Helene L.; Røise, Olav; Anke, Audny Gabriele Wagner; Røe, Cecilie; Næss, Pål Aksel; Gaarder, Aslaug Christine; Helseth, Eirik; Hestnes, Morten; Brunborg, Cathrine; Andelic, Nada; Hellstrøm, Torgeir; Dahl, Hilde Margrete (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-15)
      This study aims to evaluate the global functional outcomes after moderate-to-severe traumatic injury at 6 and 12 months and to examine the sociodemographic and injury-related factors that predict these outcomes. A prospective cohort study was conducted in which trauma patients of all ages with a New Injury Severity Score > 9 who were discharged alive from two regional trauma centres in Norway ...
    • Geriatric Trauma – a rising tide. Assessing Patient Safety challenges in a vulnerable population. The GTAPS project protocol 

      Cuevas-Østrem, Mathias; Røise, Olav; Wisborg, Torben; Jeppesen, Elisabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-17)
      <i>Background</i>: Many high- and-middle-income countries around the world are experiencing historic demographical changes: People are living longer, birth rates are decreasing, and older people constitute a growing proportion of the population. This contributes to increasing numbers of geriatric trauma patients. Geriatric patients have higher mortality rates after injury than younger patients, and ...
    • Global Characterisation of Coagulopathy in Isolated Traumatic Brain Injury (iTBI): A CENTER-TBI Analysis 

      Böhm, JK; Güting, Helge; Thorn, S; Schäfer, Nadine; Rambach, V; Schöchl, Herbert; Grottke, Oliver; Rossaint, Rolf; Stanworth, Simon; Curry, Nicola; Lefering, Rolf; Maegele, Marc; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-11)
      <i>Background</i> - Trauma-induced coagulopathy in patients with traumatic brain injury (TBI) is associated with high rates of complications, unfavourable outcomes and mortality. The mechanism of the development of TBI-associated coagulopathy is poorly understood.<br><br> <i>Methods</i> - This analysis, embedded in the prospective, multi-centred, observational Collaborative European NeuroTrauma ...
    • High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI 

      Petrosino, Matteo; Rezoagli, Emanuele; Rebora, Paola; Menon, David K.; Mondello, Stefania; Cooper, D. James; Maas, Andrew I. R.; Wiegers, Eveline J. A.; Stefania, Galimberti; Citerio, Giuseppe; Nada, Andelic; Andreassen, Lasse; Vik, Anne; Anke, Audny Gabriele Wagner; Frisvold, Shirin; Skandsen, Toril; Helseth, Eirik; Røe, Cecilie; Røise, Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-20)
      Purpose The effect of high arterial oxygen levels and supplemental oxygen administration on outcomes in traumatic brain injury (TBI) is debated, and data from large cohorts of TBI patients are limited. We investigated whether exposure to high blood oxygen levels and high oxygen supplementation is independently associated with outcomes in TBI patients admitted to the intensive care unit (ICU) and ...
    • Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury 

      Gravesteijn, BY; Nieboer, Daan; Ercole, Ari; Lingsma, Hester F; Nelson, David; Van Calster, Ben; Steyerberg, Ewout W; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-19)
      <i>Objective</i> - We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury.<br><br> <i>Study Design and Setting</i> - We performed logistic regression (LR), lasso regression, and ridge regression with key baseline predictors in the IMPACT-II database (15 studies, <i>n</i> = 11,022). ML algorithms ...
    • Post-Concussion Symptoms in Complicated vs. Uncomplicated Mild Traumatic Brain Injury Patients at Three and Six Months Post-Injury: Results from the CENTER-TBI Study 

      Voomolen, DC; Haagsma, JA; Polinder, Suzanne; Maas, AIR; Steyerberg, Ewout W; Vulekovic, Peter; Sewalt, CA; Gravesteijn, BY; Covic, Amra; Andelic, Nada; Plass, AM; von Steinbüchel, Nicole; Vik, Anne; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin Kordasti; Helseth, Eirik; Skandsen, Toril; Røise, Olav; Håberg, Asta; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-08)
      Abstract The aim of this study was to assess the occurrence of post-concussion symptoms and post-concussion syndrome (PCS) in a large cohort of patients after complicated and uncomplicated mild traumatic brain injury (mTBI) at three and six months post-injury. Patients were included through the prospective cohort study: Collaborative European NeuroTrauma Effectiveness Research (CENTER-TBI). Patients ...
    • Rehabilitation Needs, Service Provision, and Costs in the First Year Following Traumatic Injuries: Protocol for a Prospective Cohort Study 

      Søberg, Helene Lundgaard; Moksnes, Håkon Øgreid; Anke, Audny; Røise, Olav; Røe, Ellen-Cecilie Treu; Aas, Eline; Sveen, Unni; Gaarder, Christine; Næss, Pål Aksel; Helseth, Eirik; Dahl, Hilde Margrete; Becker, Frank; Løvstad, Marianne; Bartnes, Kristian; Schäfer, Christoph; Rasmussen, Mari Storli; Perrin, Paul B.; Lu, Juan; Hellstrøm, Torgeir; Hadzic-Andelic, Nada (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-14)
      Background: Traumatic injuries, defined as physical injuries with sudden onset, are a major public health problem worldwide. There is a paucity of knowledge regarding rehabilitation needs and service provision for patients with moderate and major trauma, even if rehabilitation research on a spectrum of specific injuries is available.<p> <p>Objective: This study aims to describe the prevalence of ...
    • Variation in the practice of tracheal intubation in Europe after traumatic brain injury: a prospective cohort study 

      Gravesteijn, BY; Sewalt, C.; Ercole, Ari; Lecky, Fiona; Menon, David; Steyerberg, Ewout W; Maas, AIR; Lingsma, Hester F; Klimek, Magdalena; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røise, Olav; Røe, Cecilie; Schirmer-Mikalsen, Kari; Sandrød, Oddrun; Borgen Lund, Stine (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-13)
      Traumatic brain injury patients frequently undergo tracheal intubation. We aimed to assess current intubation practice in Europe and identify variation in practice. We analysed data from patients with traumatic brain injury included in the prospective cohort study collaborative European neurotrauma effectiveness research in traumatic brain injury (CENTER‐TBI) in 45 centres in 16 European countries. ...